TLR1 (NM_003263) Human 3' UTR Clone

Specifications

Product Data
Product Name	TLR1 (NM_003263) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	CD281; rsc786; TIL; TIL. LPRS5
ACCN	NM_003263
Insert Size	246 bp
Sequence Data	Insert Sequence (showhide) >SC202772 3’UTR clone of NM_003263 The sequence shown below is from the reference sequence of NM_003263. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC ATTAAGCTGACAGAGCAAGCAAAGAAATAGATTACACATCAAGTGAAAAATATTCCTCCTGTTGATATT GCTGCTTTTGGAAGTTCCAACAATGACTTTATTTTGCATCAGCATAGATGTAAACACAATTGTGAGTGT ATGATGTAGGTAAAAATATATACCTTCGGGTCGCAGTTCACCATTTATATGTGGTATTAAAAATTAATG AAATGATATAACTTTGATTTAAACAGTTCTGACACATAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_003263.4
Synonyms	CD281; rsc786; TIL; TIL. LPRS5
Summary	The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is ubiquitously expressed, and at higher levels than other TLR genes. Different length transcripts presumably resulting from use of alternative polyadenylation site, and/or from alternative splicing, have been noted for this gene. [provided by RefSeq, Jul 2008]
Locus ID	7096
MW	9.6

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