FH (NM_000143) Human 3' UTR Clone

Specifications

Product Data
Product Name	FH (NM_000143) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	FMRD; HLRCC; HsFH; LRCC; MCL; MCUL1
ACCN	NM_000143
Insert Size	255 bp
Sequence Data	Insert Sequence (showhide) >SC202671 3’UTR clone of NM_000143 The sequence shown below is from the reference sequence of NM_000143. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC AAACCTAAGGACATGCTGGGTCCAAAGTGATTTACATAAATTTATAATGAAAATAAACATGTATAAAAT TTAAAAAAACAGACTCCCATTTCTTAAAAACGGATAAGTTTGAAAGGAAACTGCTATTGAACTTAAGCA TCTCTAGCAGAGCAATTTGATCAGTATATAAAACCCTAGGATGTGCTAGGTCTAAGATGGATTAAACAA GTATAAAATAAAATACATTTATAAAATAAAAAGGAAAACAGACTTAAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_000143.4
Synonyms	FMRD; HLRCC; HsFH; LRCC; MCL; MCUL1
Summary	The protein encoded by this gene is an enzymatic component of the tricarboxylic acid (TCA) cycle, or Krebs cycle, and catalyzes the formation of L-malate from fumarate. It exists in both a cytosolic form and an N-terminal extended form, differing only in the translation start site used. The N-terminal extended form is targeted to the mitochondrion, where the removal of the extension generates the same form as in the cytoplasm. It is similar to some thermostable class II fumarases and functions as a homotetramer. Mutations in this gene can cause fumarase deficiency and lead to progressive encephalopathy. [provided by RefSeq, Jul 2008]
Locus ID	2271
MW	10

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