PR3 (PRTN3) (NM_002777) Human 3' UTR Clone

Specifications

Product Data
Product Name	PR3 (PRTN3) (NM_002777) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	ACPA; AGP7; C-ANCA; CANCA; MBN; MBT; NP-4; NP4; P29; PR-3; PR3
ACCN	NM_002777
Insert Size	236 bp
Sequence Data	Insert Sequence (showhide) >SC202337 3’UTR clone of NM_002777 The sequence shown below is from the reference sequence of NM_002777. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC CGCCGTGTGGAGGCCAAGGGCCGCCCCTGAACCGCCCCTCCCACAGCGCTGGCCGGGACCCCGAGCCTG GCTCCAAACCCTCGAGGCGGATCTTTGGACAGAAGCAGCTCTTCCCCGAACACTGTGGCGTCCGGGACG GCCCCACCCGTCCCCCCACACTCCCTCCCACGGGGCTCCGGGAGACAGGCCGGCCCTGCACCTCACCCC ACCGTGACCTCAATAAACGTTGAAACTCC ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_002777.4
Synonyms	ACPA; AGP7; C-ANCA; CANCA; MBN; MBT; NP-4; NP4; P29; PR-3; PR3
Summary	Serine protease that degrades elastin, fibronectin, laminin, vitronectin, and collagen types I, III, and IV (in vitro) (PubMed:3198760, PubMed:2033050, PubMed:28240246). By cleaving and activating receptor F2RL1/PAR-2, enhances endothelial cell barrier function and thus vascular integrity during neutrophil transendothelial migration (PubMed:23202369). May play a role in neutrophil transendothelial migration, probably when associated with CD177 (PubMed:22266279).[UniProtKB/Swiss-Prot Function]
Locus ID	5657
MW	7.8

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