TEM8 (ANTXR1) (NM_053034) Human 3' UTR Clone

Specifications

Product Data
Product Name	TEM8 (ANTXR1) (NM_053034) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	ATR; GAPO; TEM8
ACCN	NM_053034
Insert Size	234 bp
Sequence Data	Insert Sequence (showhide) >SC202313 3’UTR clone of NM_053034 The sequence shown below is from the reference sequence of NM_053034. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC GAGGAGAGTGAGGAAAATAAAATAAAATAACAAGAAGAAGAAAGAAAGAAATCCCACAGAAACAGATAA CCTAACACAGCCCGTGCAACGTATTTTATACAATGCTCTGAAAATCATAGTCTCAATCTAGACAGTCTT TTCCTCTAGTTCCCTGTATTCAAATCCCAGTGTCTAACATTCAATAAATAGCTATATGAAATCAAAAAA AAAAAAAAAAAAAAAAAAAAAAAAAAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_053034.2
Synonyms	ATR; GAPO; TEM8
Summary	This gene encodes a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. The encoded protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell, the other two components of anthrax toxin, edema factor (EF) and lethal factor (LF) disrupt normal cellular processes. Three alternatively spliced variants that encode different protein isoforms have been described. [provided by RefSeq, Oct 2008]
Locus ID	84168
MW	9.5

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