BLM (NM_000057) Human 3' UTR Clone

Specifications

Product Data
Product Name	BLM (NM_000057) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	BS; MGRISCE1; RECQ2; RECQL2; RECQL3
ACCN	NM_000057
Insert Size	917 bp
Sequence Data	Insert Sequence (showhide) >SC201861 3’UTR clone of NM_000057 The sequence shown below is from the reference sequence of NM_000057. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC TTTCTTAAGCCTTCATATGCATTCTCATAACAACCGAATCTCAATGTACATAGACCCTCTTTCTTGTTT GTCAGCATCTGACCATCTGTGACTATAAAGCTGTTATTCTTGTTATACCATTTGAAGTTTTTACTCGTC TCTATTAATATTTAAATAAATGCTGGGGGGTGATAGTTCTTCTTTTTAAAATAAACATTTTCTTTTGAA TAAGCATGTTTTGCTGCCGCTGCAAGTGTTGTGGCCGTTGTTTCTCAGAACGTCTGAGGCAGCAGCTGA ATCATCTCAGTGCAAGAGCTTCTGAGCATAACACGAAACCCAGAAGCCAAAGGAAGAGCCACGCGTGGG CCCTTGTGAAACTAAAGCTTTTCGTGTAAGACAACACAAACAAAATTTAAAGACAAATGACGGGGAAAA GAGGAGAAAATATATTACAAAGGATTAGTATCCATCATACCAAATACCCGTGAACCAGTCAGAAACATC CCAGGGGGCAGGTGGACCAAGGATGTGAACAGGCTAGTCTCAGAAGAAGAAATACACATGCTCATGGCC CGGCACTGTGGCTCACGCCTGGGATCCCAGCACTTTGGGAGGCCGAGGCAGGTGGATCACGAGGTCAGG AGTTTGAGACCAGCCTGCCCAACATGGTGAAACCCCGTCTCTACTAAAAATACAAAAATTAGCCAGGCG TGGTGTACAGGCACGCCTGTAGTCCCAGCTACTCAGGAGGCTGAGGCAAGAGAATCGCTTGAACCCAGG AGGCGGAGGTTGCAGTGAGCCGAGATCGTGCCACTGCACTCCAGCCTGGGTGACAGAGCAAGACTCCGT CTCAAAAAAAAAAAAAAAAAAAGAAATATACATGCTCTGCAAATATGTGAAAAAGGTCAATCTCCATGA ATAAAAATATGATAAAACCA AGCGGACCGACTTACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCC CAACCTGCCATCACGAGATTTCGATTCCACCGCCGC
Restriction Sites	SgfI-RsrII
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_000057.4
Synonyms	BS; MGRISCE1; RECQ2; RECQL2; RECQL3
Summary	The Bloom syndrome is an autosomal recessive disorder characterized by growth deficiency, microcephaly and immunodeficiency among others. It is caused by homozygous or compound heterozygous mutation in the gene encoding DNA helicase RecQ protein on chromosome 15q26. This Bloom-associated helicase unwinds a variety of DNA substrates including Holliday junction, and is involved in several pathways contributing to the maintenance of genome stability. Identification of pathogenic Bloom variants is required for heterozygote testing in at-risk families. [provided by RefSeq, May 2020]
Locus ID	641
MW	34.5

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