PSMC2 (NM_002803) Human 3' UTR Clone

Specifications

Product Data
Product Name	PSMC2 (NM_002803) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	MSS1; Nbla10058; RPT1; S7
ACCN	NM_002803
Insert Size	1371 bp
Sequence Data	Insert Sequence (showhide) >SC201792 3’UTR clone of NM_002803 The sequence shown below is from the reference sequence of NM_002803. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC GCTACTCCTCGTTACATGACATACAACTGAACCCTGAAGGCTTTCAAGTGAAAACTTTAAATTGGAATC CTAACCTTATATAGACTTGTTAATAACCAATTCATAAACAAATAAATGGCTTCAAAATTGTATGCTTTT TTCCATATCTCTTCTTGTAATATAATAAAAGGTGATTTCTAATGTTATTAGGCAGAAAAGCTTGTTAGA ATATATTTTGACTATTTTTTTGACCCACACCCGTTTAAGGATTTCACATCATACAAAGCGCTTGCTTAG ATGGCTTCTATCCTAGGCATATGCTGGCCGGGTGCTCTACATATAAATTCTCATTGTATCCTCCCATCT GTCCACTGAGGAAGATTATCAAATGGATCTTCATCCAATGGATGCATAAACTTTCCTACTTACTTGTAG TGGCAAAGCTGGCTTTCAAGTACAAGTTTGTTGGCTCCATTACCTATGCTCCTATTATCCGCTTCTGTC CCGCAACAAAGTAGCTCACTTAGGCGTATGACCACATGCATTATGATAGTTTCCCACCACCATATTGAA TAATAAAAGCTTTGGCCAAAGCTTTTTTAAAGTAGGAGAAACATTGGATGTATATGTTTTGCATTGCCA TTTGATTTCAAATTAATCAGGAAGAATTAGTGATTTTAATGAGCAGTAAAGTGGTGCAATAAAGCAGAA AGAAAAATGTTCAGCCAGAAGTGAAAGACTAGTAAAAAAAGAAAAAAAAATATTTGTACATATGATCTA ATTTAGAAAGTCCAGAATTGGCTTCATACAGAAAAGTGATTACTTTCATTTTACAAATTACTTTAAAAT TTTGGTAAAGTTTCTGTTAGGCTTCTGGTCTACAGTGAGGTATTTTAAAAATAAAGGTTATATTAGAAT CCTCAACATCTCTTTAAAATTACCTCCTGTGTAACCACCACCAAATCCTATCTTCTACCACAATTACCC CTTCCCCCAATGCCAAGACCAAAGCACAATAATGAATATTTTTATTGAAGTTCGATATTCATAAATAAG TTGCAAAATAAGAGTTGGATATATTTTTAATTCACAATAGAAAAAGTTGACAACATAGAAAATGCTGCT TTGCACTGAAATACTTAAAATTATGAAAGTTTTCAAGTAAAGAAATTAAAGCCTTTTATAAAATCCAAC CAACATTCTTGATTTTTCATTTTTATGAACTTGATCAGAAAAATTCATCTTTTTTAACCCTGCCCTAAT TTTTCTTGAGGAATTAAATAGAGCAAACTATTTTCAGGTTATGCTTACAATAAAATATACTTAAGAAAA TGACTGAAGATGTATGTTTTTGAATGTTTTGATTAAATAAATGTACACATTTAGAACACA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_002803.4
Synonyms	MSS1; Nbla10058; RPT1; S7
Summary	The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity. This subunit has been shown to interact with several of the basal transcription factors so, in addition to participation in proteasome functions, this subunit may participate in the regulation of transcription. This subunit may also compete with PSMC3 for binding to the HIV tat protein to regulate the interaction between the viral protein and the transcription complex. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Mar 2011]
Locus ID	5701
MW	53.7

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