GAD67 (GAD1) (NM_013445) Human 3' UTR Clone

Specifications

Product Data
Product Name	GAD67 (GAD1) (NM_013445) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	CPSQ1; DEE89; GAD; SCP
ACCN	NM_013445
Insert Size	184 bp
Sequence Data	Insert Sequence (showhide) >SC201753 3’UTR clone of NM_013445 The sequence shown below is from the reference sequence of NM_013445. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC GACATGAGGGAGTGTTGGTTGCTACGGTGATGGGGCTCAGAGCAGAACCAAAGCATGATTGTGACCTCC AGAGGTGATGGTAACTGCACACATGGTTTCCAAGGGTCTTCCTCCTAAATTTCCAGGGGCCTCCCAAGG AAAATGGACATATTCTTTTTGGAAATAAAATACTTCTACCAACATA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_013445.4
Synonyms	CPSQ1; DEE89; GAD; SCP
Summary	This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantigen and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Deficiency in this enzyme has been shown to lead to pyridoxine dependency with seizures. Alternative splicing of this gene results in two products, the predominant 67-kD form and a less-frequent 25-kD form. [provided by RefSeq, Jul 2008]
Locus ID	2571
MW	7.2

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