GSTA3 (NM_000847) Human 3' UTR Clone

Specifications

Product Data
Product Name	GSTA3 (NM_000847) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	GSTA3-3; GTA3
ACCN	NM_000847
Insert Size	190 bp
Sequence Data	Insert Sequence (showhide) >SC201667 3’UTR clone of NM_000847 The sequence shown below is from the reference sequence of NM_000847. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC GAAGAAGCCAGAAAGATTTTCAGGTTTTAATAAAGCAGCCATGGAGGCTAAGAACATGCAAGACCAATA TTCTAAAGTTTTGCAACAATGAAGTGCTTTACTTAAGTGTTGATTGTGCCTGTTGTAAAGCTAATGAAC CCTTTCCAATTATATGCTAATTAAATAATAAAAACTCCTATTTGCTAACTTA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_000847.5
Synonyms	GSTA3-3; GTA3
Summary	Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes are involved in cellular defense against toxic, carcinogenic, and pharmacologically active electrophilic compounds. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-tranferase belonging to the alpha class genes that are located in a cluster mapped to chromosome 6. Genes of the alpha class are highly related and encode enzymes with glutathione peroxidase activity. However, during evolution, this alpha class gene diverged accumulating mutations in the active site that resulted in differences in substrate specificity and catalytic activity. The enzyme encoded by this gene catalyzes the double bond isomerization of precursors for progesterone and testosterone during the biosynthesis of steroid hormones. An additional transcript variant has been identified, but its full length sequence has not been determined. [provided by RefSeq, Jul 2008]
Locus ID	2940
MW	7.2

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