Pepsinogen II (PGC) (NM_002630) Human 3' UTR Clone

Specifications

Product Data
Product Name	Pepsinogen II (PGC) (NM_002630) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	PEPC; PGII
ACCN	NM_002630
Insert Size	171 bp
Sequence Data	Insert Sequence (showhide) >SC201532 3’UTR clone of NM_002630 The sequence shown below is from the reference sequence of NM_002630. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC AACAGAGTAGGCTTTGCCACTGCCGCCTAGACTTGCTGCCTCGACACGTGGGCTCCCCTCTTCCTCTTG ACCCTGCACCCTCCTAGGGCATTGTATCTGTCTTTCCACTCTGGATTCAGCCTTCTTTTTCTGGACTCT GGACTTTCTCTAATAATAAATAGTTCTTCTTTA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_002630.4
Synonyms	PEPC; PGII
Summary	This gene encodes an aspartic proteinase that belongs to the peptidase family A1. The encoded protein is a digestive enzyme that is produced in the stomach and constitutes a major component of the gastric mucosa. This protein is also secreted into the serum. This protein is synthesized as an inactive zymogen that includes a highly basic prosegment. This enzyme is converted into its active mature form at low pH by sequential cleavage of the prosegment that is carried out by the enzyme itself. Polymorphisms in this gene are associated with susceptibility to gastric cancers. Serum levels of this enzyme are used as a biomarker for certain gastric diseases including Helicobacter pylori related gastritis. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 1. [provided by RefSeq, Oct 2009]
Locus ID	5225
MW	6.2

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.