Cytochrome P450 2E1 (CYP2E1) (NM_000773) Human 3' UTR Clone

Specifications

Product Data
Product Name	Cytochrome P450 2E1 (CYP2E1) (NM_000773) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	CPE1; CYP2E; P450-J; P450C2E
ACCN	NM_000773
Insert Size	189 bp
Sequence Data	Insert Sequence (showhide) >SC201431 3’UTR clone of NM_000773 The sequence shown below is from the reference sequence of NM_000773. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC TACAAACTCTGTGTCATTCCCCGCTCATGAGTGTGTGGAGGACACCCTGAACCCCCCGCTTTCAAACAA GTTTTCAAATTGTTTGAGGTCAGGATTTCTCAAACTGATTCCTTTCTTTGCATATGAGTATTTGAAAAT AAATATTTTCCCAGAATATAAATAAATCATCACATGATTATTTTAACTATA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_000773.4
Synonyms	CPE1; CYP2E; P450-J; P450C2E
Summary	This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is induced by ethanol, the diabetic state, and starvation. The enzyme metabolizes both endogenous substrates, such as ethanol, acetone, and acetal, as well as exogenous substrates including benzene, carbon tetrachloride, ethylene glycol, and nitrosamines which are premutagens found in cigarette smoke. Due to its many substrates, this enzyme may be involved in such varied processes as gluconeogenesis, hepatic cirrhosis, diabetes, and cancer. [provided by RefSeq, Jul 2008]
Locus ID	1571
MW	7.4

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