Tapasin (TAPBP) (NM_172208) Human 3' UTR Clone

Specifications

Product Data
Product Name	Tapasin (TAPBP) (NM_172208) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	NGS17; TAPA; TPN; TPSN
ACCN	NM_172208
Insert Size	199 bp
Sequence Data	Insert Sequence (showhide) >SC201292 3’UTR clone of NM_172208 The sequence shown below is from the reference sequence of NM_172208. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC ACTGTAGGACTCTTTGAGCATGCTACTTAATCTATATGTTTCCTTGGGTGTAGGGATTTTAAAAAGTTA CTTAGGCAGTGCTGTCCAATAGAAAGATAATGCAAGCCACATATGTAAATTTAAATACTCTAGTACTCA CATTAAAAAAATAAGCAGAAACAGGTAAAATTAACTTAATAATATACCTTATTTAATCTAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_172208.3
Synonyms	NGS17; TAPA; TPN; TPSN
Summary	This gene encodes a transmembrane glycoprotein which mediates interaction between newly assembled major histocompatibility complex (MHC) class I molecules and the transporter associated with antigen processing (TAP), which is required for the transport of antigenic peptides across the endoplasmic reticulum membrane. This interaction is essential for optimal peptide loading on the MHC class I molecule. Up to four complexes of MHC class I and this protein may be bound to a single TAP molecule. This protein contains a C-terminal double-lysine motif (KKKAE) known to maintain membrane proteins in the endoplasmic reticulum. This gene lies within the major histocompatibility complex on chromosome 6. Alternative splicing results in three transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Locus ID	6892
MW	7.8

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