CKMT1B (NM_020990) Human 3' UTR Clone

Specifications

Product Data
Product Name	CKMT1B (NM_020990) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	CKMT; CKMT1; UMTCK
ACCN	NM_020990
Insert Size	163 bp
Sequence Data	Insert Sequence (showhide) >SC201145 3’UTR clone of NM_020990 The sequence shown below is from the reference sequence of NM_020990. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC CCCACACCTGTCATCCACACCAAGCATTAACTCCCCATCGCCAGCTGATGACTCAAGATTCCCAGGAGT TCTGCTCATTCTAATGATGGCCCATTCTACTTGCTCTGGACCTGCCCCCGCATCCCCTGCCTCCATCCT AGTAAAGACTCCTTGCTATGCTGCA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_020990.5
Synonyms	CKMT; CKMT1; UMTCK
Summary	Mitochondrial creatine (MtCK) kinase is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Many malignant cancers with poor prognosis have shown overexpression of ubiquitous mitochondrial creatine kinase; this may be related to high energy turnover and failure to eliminate cancer cells via apoptosis. Ubiquitous mitochondrial creatine kinase has 80% homology with the coding exons of sarcomeric mitochondrial creatine kinase. Two genes located near each other on chromosome 15 have been identified which encode identical mitochondrial creatine kinase proteins. [provided by RefSeq, Jul 2008]
Locus ID	1159
MW	6

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