ERCC1 (NM_202001) Human 3' UTR Clone

Specifications

Product Data
Product Name	ERCC1 (NM_202001) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	COFS4; RAD10; UV20
ACCN	NM_202001
Insert Size	867 bp
Sequence Data	Insert Sequence (showhide) >SC201094 3’UTR clone of NM_202001 The sequence shown below is from the reference sequence of NM_202001. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC AAGACCAGACACAGTGGCTTCCGCCTGTAATCCCAACATTTTGGGAGGCCAAGGCGGGAGGACTGCTTG AGGCCAGAAGTTGGAGACCAGCCTGGGCAAGTGGACACCTCATTTTTACTAAAAATAAAAAAAACTAGC TGGGCATGGTGGTGTGAGCTTGCTACGTGCCTGTAGTCTCAGCTACTGGGGAGACTGAGGTGGGAGGAT CGCTTGAGCCCAGGAGGTTGAGGCTGCAGTGAGCTATAAGCATGTTACTACGCTCCAGCCTGGGTGACA GAGCGATCCTGTCTCAAAGCAGAAGCAATCCAATGAGGAAGAATGAAACTAGATAGCTATCTCTCGCCA TATACAAAAATCAAATTAAAATGGATTACAGACTTAAATCTAAGACCTCAATGCATGAAACGTCTACAA GAAAACATTGAGAAGCTCTCCAGGACATTGAACTGGGCAGAGATTTCTTGAGTAATGCCCTATAAGCAT AGGAAACTAAAGCAAAATGGACAAATGGGATCACATCAAATTAAAAAGCTTCTAAGCCAGGTGCGGTGG CTTGGGCCTGTAATCCCAGCACTTTGAGAGGCTGAGGCGGCTGGATCACCTGAGGTCAGGAGTTTGGGA CCAGCCTGGCCAACATGGAGACACCCCATCTTTACTAAAAATACAAAAAAGTAGCCAGGTATGGTGGCA CATGCCTGTAATCCCAGCTACTTGGAAGGCTGAGGCAGGACAATCGTTTGAACCCGGGAGGTGGAGGTT GCAGTGAGCCAAGATAGCGCCATTGCACTCCAGCCTGGACAATAAGAGTGAAACTCTATCTCAAAAATT AAAAAAAAAAAAAAGAATAAAAGGCTTCTGCACAGCAAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_202001.3
Synonyms	COFS4; RAD10; UV20
Summary	The product of this gene functions in the nucleotide excision repair pathway, and is required for the repair of DNA lesions such as those induced by UV light or formed by electrophilic compounds including cisplatin. The encoded protein forms a heterodimer with the XPF endonuclease (also known as ERCC4), and the heterodimeric endonuclease catalyzes the 5' incision in the process of excising the DNA lesion. The heterodimeric endonuclease is also involved in recombinational DNA repair and in the repair of inter-strand crosslinks. Mutations in this gene result in cerebrooculofacioskeletal syndrome, and polymorphisms that alter expression of this gene may play a role in carcinogenesis. Multiple transcript variants encoding different isoforms have been found for this gene. The last exon of this gene overlaps with the CD3e molecule, epsilon associated protein gene on the opposite strand. [provided by RefSeq, Oct 2009]
Locus ID	2067
MW	33

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