alpha Defensin 1 (DEFA1) (NM_004084) Human 3' UTR Clone

Specifications

Product Data
Product Name	alpha Defensin 1 (DEFA1) (NM_004084) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	DEF1; DEFA2; HNP-1; HP-1; HP1; MRS
ACCN	NM_004084
Insert Size	151 bp
Sequence Data	Insert Sequence (showhide) >SC200996 3’UTR clone of NM_004084 The sequence shown below is from the reference sequence of NM_004084. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC CAGGGAAGACTCTGGGCATTCTGCTGCTGAGCTTGCAGAAAAAGAAAAATGAGCTCAAAATTTGCTTTG AGAGCTACAGGGAATTGCTATTACTCCTGTACCTTCTGCTCAATTTCCTTTCCTCATCCCAAATAAATG CCTTGTTACAAGA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_004084.4
Synonyms	DEF1; DEFA2; HNP-1; HP-1; HP1; MRS
Summary	Defensins are a family of antimicrobial and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. The protein encoded by this gene, defensin, alpha 1, is found in the microbicidal granules of neutrophils and likely plays a role in phagocyte-mediated host defense. Several alpha defensin genes are clustered on chromosome 8. This gene differs from defensin, alpha 3 by only one amino acid. This gene and the gene encoding defensin, alpha 3 are both subject to copy number variation. [provided by RefSeq, Oct 2014]
Locus ID	1667
MW	5.8

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