TMS1 (PYCARD) (NM_013258) Human 3' UTR Clone

Specifications

Product Data
Product Name	TMS1 (PYCARD) (NM_013258) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	ASC; CARD5; TMS; TMS-1; TMS1
ACCN	NM_013258
Insert Size	129 bp
Sequence Data	Insert Sequence (showhide) >SC200733 3’UTR clone of NM_013258 The sequence shown below is from the reference sequence of NM_013258. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC TACCTGGTGGAGGACCTGGAGCGGAGCTGAGGCTCCTTCCCAGCAACACTCCGGTCAGCCCCTGGCAAT CCCACCAAATCATCCTGAATCTGATCTTTTTATACACAATATACGAAAAGCCAGCTTGAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_013258.5
Synonyms	ASC; CARD5; TMS; TMS-1; TMS1
Summary	This gene encodes an adaptor protein that is composed of two protein-protein interaction domains: a N-terminal PYRIN-PAAD-DAPIN domain (PYD) and a C-terminal caspase-recruitment domain (CARD). The PYD and CARD domains are members of the six-helix bundle death domain-fold superfamily that mediates assembly of large signaling complexes in the inflammatory and apoptotic signaling pathways via the activation of caspase. In normal cells, this protein is localized to the cytoplasm; however, in cells undergoing apoptosis, it forms ball-like aggregates near the nuclear periphery. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Locus ID	29108
MW	4.8

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