DNA Ligase III (LIG3) (NM_002311) Human 3' UTR Clone
CAT#: SC200642
3' UTR clone of ligase III DNA ATP-dependent (LIG3) nuclear gene encoding mitochondrial protein transcript variant beta for miRNA target validation
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CNY 4,845.00
货期*
3周
规格
Cited in 10 publications. |
Product images
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经常一起买 (2)
Specifications
Product Data | |
Product Name | DNA Ligase III (LIG3) (NM_002311) Human 3' UTR Clone |
Vector | pMirTarget |
Synonyms | LIG2; LIG3alpha |
ACCN | NM_002311 |
Insert Size | 135 bp |
Sequence Data |
>SC200642 3’UTR clone of NM_002311
The sequence shown below is from the reference sequence of NM_002311. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC GGAAGAACTGTGCCAGCAGGCAGGAGATAGAACAGCCCGGCCTAGCCAGGAGAGACTGCAGGGACTCAC TCAGCTGCTGGCCCCAAGTCAAAATTTACATTAAAGGGAAAAGACCAGTCTGGGTGTGGGAATGCA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG |
Restriction Sites | SgfI-MluI |
OTI Disclaimer | Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs). |
Reference Data | |
RefSeq | NM_002311.5 |
Synonyms | LIG2; LIG3alpha |
Summary | This gene is a member of the DNA ligase family. Each member of this family encodes a protein that catalyzes the joining of DNA ends but they each have a distinct role in DNA metabolism. The protein encoded by this gene is involved in excision repair and is located in both the mitochondria and nucleus, with translation initiation from the upstream start codon allowing for transport to the mitochondria and translation initiation from a downstream start codon allowing for transport to the nucleus. Additionally, alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008] |
Locus ID | 3980 |
MW | 4.5 |
Citations (10)
The use of this cDNA Clones has been cited in the following citations: |
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Overexpression of miR‑361‑5p plays an oncogenic role in human lung adenocarcinoma through the regulation of SMAD2.
,null,
International journal of oncology
,PubMed ID 30365047
[LIG3]
|
MicroRNA-122 Mimic Improves Stroke Outcomes and Indirectly Inhibits NOS2 After Middle Cerebral Artery Occlusion in Rats
,null,
Frontiers in Neuroscience
,PubMed ID 30405345
[LIG3]
|
Mechanism of TRIM25 mediated ubiquitination of metastasis associated protein (MTA) 1 in normal liver cells.
,null,
Experimental cell research
,PubMed ID 30118695
[LIG3]
|
microRNA-212 promotes lipid accumulation and attenuates cholesterol efflux in THP-1 human macrophages by targeting SIRT1.
,null,
Gene
,PubMed ID 29174964
[LIG3]
|
microRNA-1246 mediates lipopolysaccharide-induced pulmonary endothelial cell apoptosis and acute lung injury by targeting angiotensin-converting enzyme 2
,null,
American Journal of Translational Research
,PubMed ID 28386354
[LIG3]
|
MicroRNA-200b targets protein kinase Cα and suppresses triple-negative breast cancer metastasis
,null,
Carcinogenesis
,PubMed ID 24925028
[LIG3]
|
Upregulated MicroRNA-92b Regulates the Differentiation and Proliferation of EpCAM-Positive Fetal Liver Cells by Targeting C/EBPss
,null,
PLoS ONE
,PubMed ID 23936298
[LIG3]
|
Novel MicroRNAs Regulating Proliferation and Apoptosis in Uterine Papillary Serous Carcinomas
,null,
Cancer letters
,PubMed ID 23454583
[LIG3]
|
microRNA-92a Promotes Lymph Node Metastasis of Human Esophageal Squamous Cell Carcinoma via E-Cadherin *
,null,
The Journal of Biological Chemistry
,PubMed ID 21148309
[LIG3]
|
Foxo3a Regulates Apoptosis by Negatively Targeting miR-21 *
,null,
The Journal of Biological Chemistry
,PubMed ID 20371612
[LIG3]
|
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