CHMP2A (NM_014453) Human 3' UTR Clone

Specifications

Product Data
Product Name	CHMP2A (NM_014453) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	BC-2; BC2; CHMP2; VPS2; VPS2A
ACCN	NM_014453
Insert Size	113 bp
Sequence Data	Insert Sequence (showhide) >SC200635 3’UTR clone of NM_014453 The sequence shown below is from the reference sequence of NM_014453. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC GAACGGCTTAAGAACCTGCGGAGGGACTGAGTGCCCCTGCCACTCCGAGATAACCAGTGGATGCCCAGG ATCTTTTACCACAACCCCTCTGTAATAAAAGAGATTTGACACTA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_014453.4
Synonyms	BC-2; BC2; CHMP2; VPS2; VPS2A
Summary	CHMP2A belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required for both MVB formation and regulation of cell cycle progression (Tsang et al., 2006 [PubMed 16730941]).[supplied by OMIM, Mar 2008]
Locus ID	27243
MW	4.6

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