Rabbit TNF ELISA KIT (96 T)
CNY 3,200.00
货期*
3周
规格
Specifications
Product Data | |
Description | Rabbit TNF-α Immunoassay |
Size | 96 T |
Format | 96-well strip plate |
Assay Type | Solid Phase Sandwich ELISA |
Assay Length | 4 hours |
Signal | Colorimetric |
Curve Range | 31.25-2000pg/ml |
Sample Type | Serum, plasma, Cell culture supernatant |
Sample Volume | 100 uL |
Sensitivity | 8 pg/mL. |
Reactivity | Rabbit |
Interference | No significant interference observed with available related molecules. |
Components |
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Background | TNF-α, the prototypical member of the TNF protein superfamily, is a homotrimeric type-II membrane protein . Membrane bound TNF-α is cleaved by the metalloprotease TACE/ADAM17 to generate a soluble homotrimer . Both membrane and soluble forms of TNF-α are biologically active. TNF-α is produced primarily by macrophages, but it is produced also by a broad variety of cell types including lymphoid cells, mast cells, endothelial cells,cardiac myocytes, adipose tissue, fibroblasts, and neuronal tissue. TNF-α plays a key regulatory role in inflammation and host defense against bacterial infection, notably Mycobacterium tuberculosis. The role of TNF-α in autoimmunity is underscored by blocking TNF-α action to treat rheumatoid arthritis and Crohn’s disease . |
Gene Symbol | TNF |
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