Mouse Tgfb2 ELISA KIT (96 T)
CNY 3,200.00
货期*
3周
规格
Specifications
Product Data | |
Description | Mouse TGF-β2 ELISA KIT |
Size | 96 T |
Format | 96-well strip plate |
Assay Type | Solid Phase Sandwich ELISA |
Assay Length | 4 hours |
Signal | Colorimetric |
Curve Range | 3.9-250pg/ml |
Sample Type | Serum, plasma, Cell culture supernatant |
Sample Volume | 100 uL |
Specificity | This assay recognizes both natural and recombinant mouse TGF-β2. |
Sensitivity | 2pg/ml |
Reactivity | Mouse |
Interference | No significant interference observed with available related molecules. |
Components |
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Background | TGF-β2 (Transforming Growth Factor beta 2) is one of three closely related mammalian members of the large TGF-β superfamily that share a characteristic cysteine knot structure . TGF-β1, 2 and 3 are encoded by separate genes, but are often called isoforms. They are highly pleiotropic cytokines that are proposed to act as cellular switches regulating processes such as immune function, proliferation and epithelial-mesenchymal transition. Mammalian TGF-β2 is secreted as a 395 amino acid (aa) proprotein that is processed by a furin-like convertase to generate an N-terminal latency-associated peptide (LAP, ~232 aa) and a C-terminal mature TGF-β2 (~112 aa) that remain associated via hydrogen bonding. Mature mouse and rat TGF-β2 share 100% aa sequence identity, and share 97% aa identity with human, porcine, canine, equine and bovine TGF-β2. |
Gene Symbol | Tgfb2 |
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