Human IL1RA (IL1RN) ELISA KIT (96 T)
CNY 3,200.00
货期*
3周
规格
Specifications
Product Data | |
Description | Human IL-1RA ELISA KIT |
Size | 96 T |
Format | 96-well strip plate |
Assay Type | Solid Phase Sandwich ELISA |
Assay Length | 4 hours |
Signal | Colorimetric |
Curve Range | 93.7-6000pg/ml |
Sample Type | Serum, plasma, Cell culture supernatant |
Sample Volume | 100 uL |
Specificity | This assay recognizes both natural and recombinant human IL-1Ra. |
Sensitivity | 50 pg/ml |
Reactivity | Human |
Interference | No significant interference observed with available related molecules. |
Components |
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Background | IL-1ra (IL-1 receptor antagonist) is a widely expressed acute phase protein that serves to dampen inflammation. IL-1ra binds to both IL-1 RI and IL-1 RII. It competitively inhibits IL-1 (alpha or beta) binding to IL-1 RI and does not trigger recruitment of the accessory molecule IL-1 R AcP or activation of IL-1 RI signaling. IL-1ra blocks the proinflammatory actions of IL-1 including Prostaglandin E2 and IL-6 release from endothelial cells, fever generation, thrombocytosis, the production of hepatic acute phase proteins, and neutrophil expansion and infiltration. |
Gene Symbol | IL1RN |
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