Human Serum Amyloid A (SAA1) ELISA Kit 1 x 96
CNY 5,530.00
货期*
3周
规格
Specifications
Product Data | |
Description | Human Serum Amyloid A (SAA1) ELISA Kit 1 x 96 |
Size | 1 x 96 wells |
Format | 8x12 divisible strips |
Assay Type | Sandwich |
Assay Length | 4.5 hours incubations; 0.5 hour washing and analyzing samples |
Signal | Colorimetric |
Curve Range | 3.125ng/ml-200ng/ml |
Sample Type | Human serum, plasma and other biological fluids. |
Sample Volume | 100µl |
Specificity | This kit is used for quantitative detection of Human SAA1 |
Sensitivity | 0.3ng/ml |
Reactivity | Human |
Cross Reactivity | There is no detectable cross-reactivity with other relevant proteins. |
Interference | No significant interference observed with available related molecules. |
Components |
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Background | Serum amyloid A1 (SAA1) is a major acute-phase protein mainly produced by hepatocytes in response to infection, tissue injury and malignancy. When released into blood circulation, SAA1 is present as an apolipoprotein associated with high-density lipoprotein (HDL). SAA1 is a major precursor of amyloid A (AA), the deposit of which leads to inflammatory amyloidosis. Mature SAA1 consists of 104 amino acids with an apparent molecular weight of 12,500. Native SAA1 is a hexamer with each subunit assuming an antiparallel 4-helix bundle structure. Inflammatory cytokines such as IL-1β, IL-6 and TNF-α are major stimulants for hepatocyte expression of the SAA1 gene. SAA1 has been a clinical indicator and reliable biomarker for inflammatory diseases, chronic metabolic disorders and late-stage malignancy. |
Gene Symbol | SAA1 |
Standard Curve |
Serum Amyloid A (SAA1) ELISA Kit data image.
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