Equine TGFB2 ELISA KIT (1 x 96 wells)

Specifications

Product Data
Description	Sandwich High Sensitivity ELISA kit for Quantitative Detection of activated horse equine TGF-beta 2. 96wells/kit, with removable strips.
Size	1 x 96 wells
Format	8x12 divisible strips
Assay Type	Sandwich ELISA kit of Quantitative Detection for Equine TGFB2
Assay Length	3.5 hours incubations; 1 hour washing and analyzing samples
Signal	Colorimetric
Curve Range	31.2pg/ml-2000pg/ml
Specificity	This kit is used for quantitative detection of Equine TGFB2
Sensitivity	<10pg/ml
Reactivity	Equine
Cross Reactivity	There is no detectable cross-reactivity with other relevant proteins.
Components	10ng/tube
Background	Transforming growth factor-beta 2(TGF-beta 2) is a secreted protein known as a cytokine that performs many cellular functions and has a vital role during embryonic development. This gene is mapped to 1q41. It is an extracellular glycosylated protein. It is known to suppress the effects of interleukin dependent T-cell tumors. TGF-beta 2 is present at elevated levels in the aqueous humor of patients with primary open angle glaucoma(POAG). Studies have shown that TGF-beta 2 influences cultured trabecular meshwork cells, and it reduced outflow facility when perfused into cultured horse equine anterior segments. In POAG, elevated expression of Gremlin by TM cells inhibited BMP4 antagonism of TGF-beta 2 and led to increased extracellular matrix deposition and elevated IOP.
Gene Symbol	TGFB2

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