Human ULBP1 ELISA KIT (1 x 96 wells)
CAT#: EA102487
For quantitative detection of human ULBP1 in cell culture supernates, serum and plasma (heparin, EDTA).
CNY 5,000.00
货期*
3周
规格
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Specifications
Product Data | |
Description | For quantitative detection of human ULBP1 in cell culture supernates, serum and plasma (heparin, EDTA). |
Size | 1 x 96 wells |
Format | 8x12 divisible strips |
Assay Type | Sandwich ELISA kit of Quantitative Detection for Human ULBP1 |
Assay Length | 3.5 hours incubations; 1 hour washing and analyzing samples |
Signal | Colorimetric |
Curve Range | 93.7pg/ml-6000pg/ml |
Specificity | This kit is used for quantitative detection of Human ULBP1 |
Sensitivity | <10pg/ml |
Reactivity | Human |
Cross Reactivity | There is no detectable cross-reactivity with other relevant proteins. |
Components |
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Background | UL16 binding protein 1 (ULBP1) is a cell surface glycoprotein encoded by ULBP1 gene located on the chromosome 6. ULBP1 is related to MHC class I molecules, but its gene maps outside the MHC locus. The protein encoded by this gene is a ligand of natural killer group 2, member D (NKG2D), an immune system-activating receptor on NK cells and T-cells. Binding of the encoded ligand to NKG2D leads to activation of several signal transduction pathways, including those of JAK2, STAT5, ERK and PI3K kinase/Akt. Also, in cytomegalovirus-infected cells, this ligand binds the UL16 glycoprotein and is prevented from activating the immune system. Three transcript variants encoding different isoforms have been found for this gene. |
Gene Symbol | ULBP1 |
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