Human IL-15 ELISA Kit, 1 x 96-well (pre-coated)

Specifications

Product Data
Description	Human IL-15 ELISA Kit, 1 x 96-well (pre-coated)
Size	1 x 96 wells (pre-coated)
Format	1 x 96-well (pre-coated)
Assay Type	Solid Phase Sandwich ELISA
Assay Length	3h45min
Signal	Colorimetric
Curve Range	31.25-1000 pg/ml
Sample Type	Serum, Plasma, Cell culture supernatant
Sample Volume	50 µl
Specificity	Recognizes both natural and recombinant human IL-15
Sensitivity	18.3 pg/ml
Cross Reactivity	No cross reaction with IL-2, IL-4, IL-7, IL-9, IL-10, IL-13, IL-21 and IFN-g
Components	ELISA Kits include pre-coated strip plates, biotinylated secondary antibody, standards, controls (where applicable), buffers, streptavidin-HRP, TMB, stop reagents, and a detailed procedure.
Background	The protein encoded by this gene is a cytokine that regulates T and natural killer cell activation and proliferation. This cytokine and interleukine 2 share many biological activities. They are found to bind common hematopoietin receptor subunits, and may compete for the same receptor, and thus negatively regulate each other's activity. The number of CD8+ memory cells is shown to be controlled by a balance between this cytokine and IL2. This cytokine induces the activation of JAK kinases, as well as the phosphorylation and activation of transcription activators STAT3, STAT5, and STAT6. Studies of the mouse counterpart suggested that this cytokine may increase the expression of apoptosis inhibitor BCL2L1/BCL-x(L), possibly through the transcription activation activity of STAT6, and thus prevent apoptosis. Alternatively spliced transcript variants of this gene have been reported. [provided by RefSeq, Feb 2011]
Gene Symbol	IL15
Standard Curve	Representative Standard Curve

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