Human IL-13 ELISpot Pair, 10 x 96-well

Specifications

Product Data
Description	Human IL-13 ELISpot Pair, 10 x 96-well
Size	10 x 96 wells
Format	10 x 96-well
Assay Type	Enzyme-Linked ImmunoSpot (ELISpot)
Signal	Colorimetric
Specificity	Recognizes both natural and recombinant human IL-13
Cross Reactivity	No cross reactivity with other human cytokines
Components	ELISpot matched antibody pairs are extensively validated and include pre-titrated capture antibody and biotinylated detection antibody. Antibodies are supplied in quantities sufficient for 10 x 96 samples.
Background	This gene encodes an immunoregulatory cytokine produced primarily by activated Th2 cells. This cytokine is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils. This gene, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL4. [provided by RefSeq, Jul 2008]
Gene Symbol	IL13

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