Human CD25 ELISA Set, 20 x 96-well

Specifications

Product Data
Description	Human CD25 ELISA Set, 20 x 96-well
Size	20 x 96 wells
Format	20 x 96-well
Assay Type	Solid Phase Sandwich ELISA
Assay Length	From sample to end 2h15min
Signal	Colorimetric
Curve Range	68.75-2220 pg/ml
Sample Type	Serum, Plasma, Cell culture supernatant
Sample Volume	100 µl
Specificity	Recognizes both natural and recombinant human soluble IL-2R
Sensitivity	8 pg/ml
Cross Reactivity	No cross reactivity with other human soluble receptors
Components	ELISA Sets include capture and biotinylated detection antibody, one standard per plate, Streptavidin-HRP, TMB, and detailed procedure including buffer composition.
Background	The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency. [provided by RefSeq, Nov 2009]
Gene Symbol	IL2RA

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