Human MICA ELISA Kit, 1 x 48-well (pre-coated)

Specifications

Product Data
Description	Human MICA ELISA Kit, 1 x 48-well (pre-coated)
Size	1 x 48 wells (pre-coated)
Format	1 x 48-well (pre-coated)
Assay Type	Solid Phase Sandwich ELISA
Assay Length	3h50min
Signal	Colorimetric
Curve Range	156-5000 pg/ml
Sample Type	Supernatant, Buffered Solutions. Not suitable for use with serum and plasma.
Sample Volume	100 µl
Specificity	Recognizes both natural and recombinant human MICA
Sensitivity	123 pg/ml
Cross Reactivity	No cross reactivity with IL-7, IL-12p40, IL-2R, Trail, CD31, IL-13Ra2, IL-5, gp130, TNFa.
Interference	No significant interference observed with available related molecules.
Components	ELISA Kits include pre-coated strip plates, biotinylated secondary antibody, standards, controls (where applicable), buffers, streptavidin-HRP, TMB, stop reagents, and a detailed procedure.
Background	This gene encodes the highly polymorphic major histocompatability complex class I chain-related protein A. The protein product is expressed on the cell surface, although unlike canonical class I molecules it does not seem to associate with beta-2-microglobulin. It is a ligand for the NKG2-D type II integral membrane protein receptor. The protein functions as a stress-induced antigen that is broadly recognized by intestinal epithelial gamma delta T cells. Variations in this gene have been associated with susceptibility to psoriasis 1 and psoriatic arthritis, and the shedding of MICA-related antibodies and ligands is involved in the progression from monoclonal gammopathy of undetermined significance to multiple myeloma. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jan 2014]
Gene Symbol	MICA
Standard Curve	Representative Standard Curve

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