Rat Cystatin C ELISA Kit
CNY 5,000.00
货期*
3周
规格
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Specifications
Product Data | |
Description | Rat Cystatin C ELISA Kit |
Size | 1 x 96 wells |
Assay Type | Sandwich ELISA kit of Quantitative Detection for Rat Cystatin C |
Assay Length | 3.5 hours incubations; 1 hour washing and analyzing samples |
Signal | Colorimetric |
Curve Range | 312pg/ml-20,000pg/ml |
Sample Type | Cell culture supernates, serum, plasma(heparin, EDTA) and urine. |
Sample Volume | 100 ul |
Specificity | This kit is used for quantitative detection of rat Cystatin C |
Sensitivity | <10pg/ml |
Reactivity | Rat |
Cross Reactivity | There is no detectable cross-reactivity with other relevant proteins. |
Interference | No significant interference observed with available related molecules. |
Components |
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Background | Cystatin C or cystatin 3(formerly gamma trace, post-gamma-globulin or neuroendocrine basic polypeptide), a protein encoded by the CST3 gene, was originally described as a constituent of normal cerebrospinal fluid(CSF) and of urine from patients with renal failure. Cystatin 3 has a low molecular weight(approximately 13.3 kilodaltons), and it is removed from the bloodstream by glomerular filtration in the kidneys. In mouses, all cells with a nucleus(cell core containing the DNA) produce cystatin C as a chain of 120 amino acids. It is found in virtually all tissues and bodily fluids. Cystatin C, which belongs to the type II cystatin gene family, is a potent inhibitor of lysosomal proteinases(enzymes from a special subunit of the cell that break down proteins) and probably one of the most important extracellular inhibitors of cysteine proteases(it prevents the breakdown of proteins outside the cell by a specific type of protein degrading enzymes). Moreover, cystatin C is involved in network reorganization in the epileptic dentate gyrus. |
Gene Symbol | Cst3 |
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