Mouse TGF-beta 2 ELISA Kit
CNY 5,000.00
货期*
3周
规格
Cited in 1 publication. |
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Specifications
Product Data | |
Description | Mouse TGF-beta 2 ELISA Kit |
Size | 1 x 96 wells |
Assay Type | Sandwich ELISA kit of Quantitative Detection for Mouse TGF-beta 2 |
Assay Length | 3.5 hours incubations; 1 hour washing and analyzing samples |
Signal | Colorimetric |
Curve Range | 31.2pg/ml-2000pg/ml |
Sample Type | Cell culture supernates, serum and plasma(heparin, EDTA, citrate). |
Sample Volume | 100 ul |
Specificity | This kit is used for quantitative detection of activated mouse TGF-beta 2 |
Sensitivity | <10pg/ml |
Reactivity | Mouse |
Cross Reactivity | There is no detectable cross-reactivity with other relevant proteins. |
Interference | No significant interference observed with available related molecules. |
Components |
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Background | Transforming growth factor-beta 2(TGF-beta 2) is a secreted protein known as a cytokine that performs many cellular functions and has a vital role during embryonic development. This gene is mapped to 1q41. It is an extracellular glycosylated protein. It is known to suppress the effects of interleukin dependent T-cell tumors. TGF-beta 2 is present at elevated levels in the aqueous humor of patients with primary open angle glaucoma(POAG). Studies have shown that TGF-beta 2 influences cultured trabecular meshwork cells, and it reduced outflow facility when perfused into cultured human anterior segments. In POAG, elevated expression of Gremlin by TM cells inhibited BMP4 antagonism of TGF-beta 2 and led to increased extracellular matrix deposition and elevated IOP. |
Gene Symbol | Tgfb2 |
Citations (1)
The use of this Assay Kits has been cited in the following citations: |
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Evaluation of pro‑ and anti‑tumor effects induced by three colony‑stimulating factors, G‑CSF, GM‑CSF and M‑CSF, in bladder cancer cells: Is G‑CSF a friend of bladder cancer cells?
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International journal of oncology
,PubMed ID 31081057
[Tgfb2]
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