Mouse CXCL10/IP-10 ELISA Kit

Specifications

Product Data
Description	Mouse CXCL10/IP-10 ELISA Kit
Size	1 x 96 wells
Assay Type	Sandwich ELISA kit of Quantitative Detection for Mouse CXCL10/IP-10
Assay Length	3.5 hours incubations; 1 hour washing and analyzing samples
Signal	Colorimetric
Curve Range	31.2pg/ml-2000pg/ml
Sample Type	Cell culture supernates, serum and plasma(heparin).
Sample Volume	100 ul
Specificity	This kit is used for quantitative detection of mouse CXCL10
Sensitivity	<1pg/ml
Reactivity	Mouse
Cross Reactivity	There is no detectable cross-reactivity with other relevant proteins.
Interference	No significant interference observed with available related molecules.
Components	96-well plate precoated with anti- mouse Cxcl10 antibody | 1 Lyophilized recombinant mouse Cxcl10 standard | 10ng/tubex2 Biotinylated anti- mouse Cxcl10 antibody | 100ul (dilution 1:100) Avidin-Biotin-Peroxidase Complex(ABC) | 100ul (dilution 1:100) Sample diluent buffer | 30 ml Antibody diluent buffer | 12ml ABC diluent buffer | 12ml TMB color developing agent |10ml TMB stop solution | 10ml Plate Sealers | 4 piece Wash Buffer powder | 1 Pack
Background	Chemokine(C-X-C motif) ligand 10(CXCL10) or IP-10 is a small cytokine belonging to the CXC chemokine family that is also known as 10 kDa interferon-gamma-induced protein(gamma-IP10 or IP-10). CXCL10 is secreted by several cell types in response to IFN-gamma. These cell types include monocytes, endothelial cells and fibroblasts. CXCL10 has been attributed to several roles, such as chemoattraction for monocytes/macrophages, T cells, NK cells, and dendritic cells, promotion of T cell adhesion to endothelial cells, antitumor activity, and inhibition of bone marrow colony formation and angiogenesis.It is a potent inhibitor of angiogenesis in vivo. The gene for CXCL10 is located on human chromosome 4 in a cluster among several other CXC chemokines. It is a RAS target gene and is overexpressed in the majority of colorectal cancers.This chemokine elicits its effects by binding to the cell surface chemokine receptor CXCR3.
Gene Symbol	Cxcl10

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