Rat TIMP-1 ELISA Kit
CNY 5,230.00
货期*
3周
规格
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Specifications
Product Data | |
Description | Rat TIMP-1 ELISA Kit |
Size | 1 x 96 wells |
Assay Type | Sandwich ELISA kit of Quantitative Detection for Rat TIMP-1 |
Assay Length | 3.5 hours incubations; 1 hour washing and analyzing samples |
Signal | Colorimetric |
Curve Range | 31.2pg/ml-2000pg/ml |
Sample Type | Cell culture supernates, serum and plasma(heparin, EDTA). |
Sample Volume | 100 ul |
Specificity | This kit is used for quantitative detection of rat TIMP-1 |
Sensitivity | <3pg/ml |
Reactivity | Rat |
Cross Reactivity | There is no detectable cross-reactivity with other relevant proteins. |
Interference | No significant interference observed with available related molecules. |
Components |
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Background | The tissue inhibitor of metalloproteinases 1(TIMP1) is also called erythroid-potentiating activity(EPA). The X-linked gene for human TIMP1 is expressed in some but not all inactive X-containing somatic-cell hybrids, suggesting that this gene is either prone to reactivation or variable in its inactivation.1 Purified EPA specifically stimulates human and murine cells of the erythroid lineage, unlike murine interleukin-3(IL-3) which stimulates precursor cells from all haematopoietic lineages.2 TIMP1 is thought to play a regulatory role in connective tissues by forming inactive complexes with those metalloproteinases that are normally responsible for connective tissue turnover. The human gene encoding TIMP has been mapped to the X chromosome in the region Xp11.1-p11.4.3 The standard product used in this kit is recombinant rat TIMP-1, consisting of 194 amino acids with the molecular mass of 21.5KDa. As a result of glycosylation, the molecular mass is 32-34KDa. |
Gene Symbol | Timp1 |
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