Fasl
CNY 5,560.00
货期*
3周
规格
Cited in 1 publication. |
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Specifications
Product Data | |
Description | Human FASL ELISA Kit |
Size | 1 x 96 wells |
Assay Type | Sandwich ELISA kit of Quantitative Detection for Human FASL |
Assay Length | 3.5 hours incubations; 1 hour washing and analyzing samples |
Signal | Colorimetric |
Curve Range | 15.6pg/ml-1000pg/ml |
Sample Type | Cell culture supernates, serum and plasma(heparin, EDTA, citrate). |
Sample Volume | 100 ul |
Specificity | This kit is used for quantitative detection of human FASL |
Sensitivity | <2pg/ml |
Reactivity | Human |
Cross Reactivity | There is no detectable cross-reactivity with other relevant proteins. |
Interference | No significant interference observed with available related molecules. |
Components |
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Background | Fas ligand(FasL or CD95L) is a type-II transmembrane protein that belongs to the tumor necrosis factor(TNF) family. Its binding with its receptor induces apoptosis. The human FASL gene consists of approximately 8 kb and is split into 4 exons. Fas ligand/receptor interactions play an important role in the regulation of the immune system and the progression of cancer. Fas ligand or FasL is a homotrimeric type II transmembrane protein. It signals through trimerization of FasR, which spans the membrane of the "target" cell. This trimerization usually leads to apoptosis, or cell death. Soluble Fas ligand is generated by cleaving membrane-bound FasL at a conserved cleavage site by the external matrix metalloproteinase MMP-7. |
Gene Symbol | Fasl |
Citations (1)
The use of this Assay Kits has been cited in the following citations: |
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Targeting the IL-1β/IL-1Ra pathways for the aggregation of human islet amyloid polypeptide in an ex vivo organ culture system of the intervertebral disc
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Experimental & Molecular Medicine
,PubMed ID 31554783
[Fasl]
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