PAX2 Rabbit Monoclonal Antibody [Clone ID: UMAB301]

Specifications

Product Data
Clone Name	UMAB301
Applications	IHC
Recommend Dilution	IHC 1:250
Reactivity	Human
Host	Rabbit
Clonality	Monoclonal
Immunogen	Human recombinant protein fragment of human PAX2 (NP_003978) produced in E.coli.
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	1.00mg/ml
Purification	Purified from cell culture supernatant by affinity chromatography(protein A/G)
Conjugation	Unconjugated
Predicted Protein Size	44.5 kDa
Gene Name	paired box 2
Database Link	NP_003978 Entrez Gene 5076 Human UniProt ID Q02962
Background	PAX2 encodes paired box gene 2, one of many human homologues of the Drosophila melanogaster gene prd. The central feature of this transcription factor gene family is the conserved DNA-binding paired box domain. PAX2 is believed to be a target of transcriptional supression by the tumor suppressor gene WT1. Mutations within PAX2 have been shown to result in optic nerve colobomas and renal hypoplasia. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Dec 2014]
Synonyms	FSGS7; PAPRS
Reference Data
Protein Families	Druggable Genome

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