Folate Binding Protein (FOLR1) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB 1:2000
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	Human recombinant protein fragment of human FOLR1 ( NP_057937 ) produced in HEK293T.
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	1 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	29.82 kDa
Gene Name	folate receptor 1 (adult)
Database Link	NP_057937 Entrez Gene 2348 Human UniProt ID P15328
Background	The protein encoded by this gene is a member of the folate receptor family. Members of this gene family bind folic acid and its reduced derivatives, and transport 5-methyltetrahydrofolate into cells. This gene product is a secreted protein that either anchors to membranes via a glycosyl-phosphatidylinositol linkage or exists in a soluble form. Mutations in this gene have been associated with neurodegeneration due to cerebral folate transport deficiency. Due to the presence of two promoters, multiple transcription start sites, and alternative splicing, multiple transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Oct 2009]
Synonyms	FBP; FOLR; FRalpha; NCFTD
Reference Data
Protein Families	Druggable Genome, Secreted Protein, Transmembrane

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