TREM2 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB 1:2000
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	Full length human recombinant protein of human TREM2 (NP_061838) produced in Expi 293F.
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	1 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	23.4 kDa
Gene Name	triggering receptor expressed on myeloid cells 2
Database Link	NP_061838 Entrez Gene 54209 Human UniProt ID Q9NZC2
Background	This gene encodes a membrane protein that forms a receptor signaling complex with the TYRO protein tyrosine kinase binding protein. The encoded protein functions in immune response and may be involved in chronic inflammation by triggering the production of constitutive inflammatory cytokines. Defects in this gene are a cause of polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Nov 2012]
Synonyms	PLOSL2; TREM-2; Trem2a; Trem2b; Trem2c
Reference Data
Protein Families	Druggable Genome, Secreted Protein, Transmembrane

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