SOCS1 Rabbit Polyclonal Antibody

CAT#: TA890038

Rabbit polyclonal anti-SOCS1 Antibody

Size: 30 ul 100 ul



 

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CNY 1,999.00

CNY 2,700.00


货期*
现货

规格
    • 100 ul

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经常一起买 (4)
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Recombinant protein of human suppressor of cytokine signaling 1 (SOCS1), 100 µg
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Specifications

Product Data
Applications WB
Recommend Dilution WB: 1:500~1:1000
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Immunogen Recombinant protein of human SOCS1
Formulation PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Concentration 0.97mg/ml
Purification Purified from the immunized serum by affinity chromatography (Protein A/G)
Conjugation Unconjugated
Storage Condition Store at -20°C as received.
Predicted Protein Size 23.4 kDa
Gene Name suppressor of cytokine signaling 1
Background This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by a subset of cytokines, including IL2, IL3 erythropoietin (EPO), CSF2/GM-CSF, and interferon (IFN)-gamma. The protein encoded by this gene functions downstream of cytokine receptors, and takes part in a negative feedback loop to attenuate cytokine signaling. Knockout studies in mice suggested the role of this gene as a modulator of IFN-gamma action, which is required for normal postnatal growth and survival. [provided by RefSeq, Jul 2008]
Synonyms CIS1; CISH1; JAB; SOCS-1; SSI-1; SSI1; TIP3
Reference Data
Protein Families Druggable Genome, Stem cell - Pluripotency, Stem cell relevant signaling - JAK/STAT signaling pathway
Protein Pathways Insulin signaling pathway, Jak-STAT signaling pathway, Type II diabetes mellitus, Ubiquitin mediated proteolysis
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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