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Perforin (PRF1) Mouse Monoclonal Antibody [Clone ID: OTI3D7]
CAT＃: TA814190
Perforin-1 mouse monoclonal antibody, clone OTI3D7
Size: 30 ul
Formulation: Carrier Free
View other "OTI3D7" antibodies (4)
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CNY 1,999.00
CNY 3,600.00
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CNY 3,080.00
CNY 300.00
CNY 1,430.00
Specifications
| Product Data | |
| Clone Name | OTI3D7 |
| Applications | IHC |
| Recommend Dilution | IHC 1:100 |
| Reactivity | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 351-555 of human Perforin-1 (NP_005032) produced in E.coli. |
| Formulation | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
| Concentration | 1 mg/ml |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | Unconjugated |
| Storage Condition | Shipped at -20°C or with ice packs, Upon delivery store at -20°C. Dilute in PBS(pH7.3) if necessary. Stable for 12 months from date of receipt. Avoid repeated freeze-thaws. |
| Predicted Protein Size | 61.38 kDa |
| Gene Name | perforin 1 |
| Database Link | |
| Background | This gene encodes a protein with structural similarities to complement component C9 that is important in immunity. This protein forms membrane pores that allow the release of granzymes and subsequent cytolysis of target cells. Whether pore formation occurs in the plasma membrane of target cells or in an endosomal membrane inside target cells is subject to debate. Mutations in this gene are associated with a variety of human disease including diabetes, multiple sclerosis, lymphomas, autoimmune lymphoproliferative syndrome (ALPS), aplastic anemia, and familial hemophagocytic lymphohistiocytosis type 2 (FHL2), a rare and lethal autosomal recessive disorder of early childhood. [provided by RefSeq, Aug 2017] |
| Synonyms | HPLH2; P1; PFP |
| Reference Data | |
| Protein Families | Druggable Genome |
| Protein Pathways | Allograft rejection, Autoimmune thyroid disease, Graft-versus-host disease, Natural killer cell mediated cytotoxicity, Type I diabetes mellitus, Viral myocarditis |
Documents
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Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| CF814190 | Carrier-free (BSA/glycerol-free) Perforin-1 mouse monoclonal antibody, clone OTI3D7 |
CNY 3,999.00 |
|
| TA814190AM | Perforin-1 mouse monoclonal antibody, clone OTI3D7, Biotinylated |
CNY 3,990.00 |
|
| TA814190BM | Perforin-1 mouse monoclonal antibody, clone OTI3D7, HRP conjugated |
CNY 3,990.00 |
|
| TA814190S | Perforin-1 mouse monoclonal antibody, clone OTI3D7 |
CNY 800.00 |
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