CD16 (FCGR3A) Mouse Monoclonal Antibody [Clone ID: OTI12D8]
CAT#: TA813633S
FCGR3A mouse monoclonal antibody, clone OTI12D8
Size: 100 ul
View other "OTI12D8" antibodies (4)
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CNY 800.00
CNY 300.00
CNY 1,430.00
CNY 2,900.00
CNY 6,650.00
CNY 3,080.00
Specifications
Product Data | |
Clone Name | OTI12D8 |
Applications | FC, WB |
Recommend Dilution | WB 1:1000, FLOW 1:100 |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Immunogen | Full length human recombinant protein of human FCGR3A (NP_001121065) produced in HEK293T cell. |
Formulation | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
Concentration | 1 mg/ml |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Unconjugated |
Storage Condition | Shipped at -20°C or with ice packs, Upon delivery store at -20°C. Dilute in PBS(pH7.3) if necessary. Stable for 12 months from date of receipt. Avoid repeated freeze-thaws. |
Predicted Protein Size | 29.09 kDa |
Gene Name | Fc fragment of IgG receptor IIIa |
Database Link | |
Background | This gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other other antibody-dependent responses. This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded by this gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. Mutations in this gene have been linked to susceptibility to recurrent viral infections, susceptibility to systemic lupus erythematosus, and alloimmune neonatal neutropenia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]. |
Synonyms | CD16; CD16A; FCG3; FCGR3; FCGRIII; FCR-10; FCRIII; FCRIIIA; IGFR3; IMD20 |
Reference Data | |
Protein Families | ES Cell Differentiation/IPS, Secreted Protein, Transmembrane |
Protein Pathways | Fc gamma R-mediated phagocytosis, Natural killer cell mediated cytotoxicity, Systemic lupus erythematosus |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
CF813633 | Carrier-free (BSA/glycerol-free) FCGR3A mouse monoclonal antibody, clone OTI12D8 |
CNY 3,999.00 |
|
TA813633 | FCGR3A mouse monoclonal antibody, clone OTI12D8 |
CNY 1,999.00 |
|
TA813633AM | FCGR3A mouse monoclonal antibody, clone OTI12D8, Biotinylated |
CNY 3,990.00 |
|
TA813633BM | FCGR3A mouse monoclonal antibody, clone OTI12D8, HRP conjugated |
CNY 3,990.00 |