TNFSF9 Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI4G5]

CAT#: TA813214AM

CD137L mouse monoclonal antibody,clone OTI4G5, Biotinylated

Conjugation: Unconjugated Biotin HRP



  View other "OTI4G5" antibodies (4)

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CNY 3,990.00


货期*
2周

规格
    • 100 ul

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Recombinant protein of human tumor necrosis factor (ligand) superfamily, member 9 (TNFSF9), 20 µg
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Specifications

Product Data
Clone Name OTI4G5
Applications FC
Recommend Dilution FLOW 1:100
Reactivity Human
Host Mouse
Clonality Monoclonal
Immunogen Full length human recombinant protein of human CD137L (NP_003802) produced in HEK293T cell.
Formulation PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration 0.5 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Biotin
Storage Condition Store at -20°C as received.
Predicted Protein Size 26.4 kDa
Gene Name tumor necrosis factor superfamily member 9
Background The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This transmembrane cytokine is a bidirectional signal transducer that acts as a ligand for TNFRSF9/4-1BB, which is a costimulatory receptor molecule in T lymphocytes. This cytokine and its receptor are involved in the antigen presentation process and in the generation of cytotoxic T cells. The receptor TNFRSF9/4-1BB is absent from resting T lymphocytes but rapidly expressed upon antigenic stimulation. The ligand encoded by this gene, TNFSF9/4-1BBL, has been shown to reactivate anergic T lymphocytes in addition to promoting T lymphocyte proliferation. This cytokine has also been shown to be required for the optimal CD8 responses in CD8 T cells. This cytokine is expressed in carcinoma cell lines, and is thought to be involved in T cell-tumor cell interaction. [provided by RefSeq, Oct 2008]
Synonyms 4-1BB-L; CD137L; TNLG5A
Reference Data
Protein Families Druggable Genome, Transmembrane
Protein Pathways Cytokine-cytokine receptor interaction
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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