p75 NGF Receptor (NGFR) Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI12E11]

Specifications

Product Data
Clone Name	OTI12E11
Applications	FC, WB
Recommend Dilution	WB 1:500, FLOW 1:100
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Full length human recombinant protein of human Ngfr (NP_002498) produced in HEK293T cell.
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	0.5 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Biotin
Storage Condition	Store at -20°C as received.
Predicted Protein Size	45.18 kDa
Gene Name	nerve growth factor receptor
Database Link	NP_002498 Entrez Gene 18053 MouseEntrez Gene 24596 RatEntrez Gene 4804 Human UniProt ID P08138
Background	Nerve growth factor receptor contains an extracellular domain containing four 40-amino acid repeats with 6 cysteine residues at conserved positions followed by a serine/threonine-rich region, a single transmembrane domain, and a 155-amino acid cytoplasmic domain. The cysteine-rich region contains the nerve growth factor binding domain. [provided by RefSeq, Jul 2008]
Synonyms	CD271; Gp80-LNGFR; p75(NTR); p75NTR; TNFRSF16
Reference Data
Protein Families	Druggable Genome, Transmembrane
Protein Pathways	Cytokine-cytokine receptor interaction, Neurotrophin signaling pathway

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