PSMA1 Mouse Monoclonal Antibody [Clone ID: OTI6C4]

Specifications

Product Data
Clone Name	OTI6C4
Applications	IF, WB
Recommend Dilution	WB 1:250
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Full length human recombinant protein of human PSMA1 (NP_002777) produced in E.coli.
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	1 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	29.4 kDa
Gene Name	proteasome subunit alpha 1
Database Link	NP_002777 Entrez Gene 26440 MouseEntrez Gene 29668 RatEntrez Gene 5682 Human UniProt ID P25786
Background	The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jan 2009]
Synonyms	HC2; HEL-S-275; NU; PROS30
Reference Data
Protein Families	Druggable Genome, Protease
Protein Pathways	Proteasome

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