TNFRSF4 Mouse Monoclonal Antibody [Clone ID: OTI2B7]

Specifications

Product Data
Clone Name	OTI2B7
Applications	FC, WB
Recommend Dilution	WB 1:500, FLOW 1:100
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Full length human recombinant protein of human TNFRSF4 (NP_003318) produced in HEK293T cell.
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	1 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	29.34 kDa
Gene Name	tumor necrosis factor receptor superfamily member 4
Database Link	NP_003318 Entrez Gene 7293 Human UniProt ID P43489
Background	The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4+ T cell response, as well as in T cell-dependent B cell proliferation and differentiation. [provided by RefSeq, Jul 2008]
Synonyms	ACT35; CD134; IMD16; OX40; TXGP1L
Reference Data
Protein Families	Transmembrane
Protein Pathways	Cytokine-cytokine receptor interaction

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