TFEC Mouse Monoclonal Antibody (HRP conjugated) [Clone ID: OTI2A9]

Specifications

Product Data
Clone Name	OTI2A9
Applications	WB
Recommend Dilution	WB 1:2000
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Full length human recombinant protein of human TFEC (NP_001018068) produced in E.coli.
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol.
Concentration	0.5 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	HRP
Storage Condition	Store at -20°C as received.
Gene Name	transcription factor EC
Database Link	NP_001018068 Entrez Gene 22797 Human UniProt ID O14948
Background	This gene encodes a member of the micropthalmia (MiT) family of basic helix-loop-helix leucine zipper transcription factors. MiT transcription factors regulate the expression of target genes by binding to E-box recognition sequences as homo- or heterodimers, and play roles in multiple cellular processes including survival, growth and differentiation. The encoded protein is a transcriptional activator of the nonmuscle myosin II heavy chain-A gene, and may also co-regulate target genes in osteoclasts as a heterodimer with micropthalmia-associated transcription factor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011]
Synonyms	bHLHe34; hTFEC-L; TCFEC; TFE-C; TFEC-L; TFECL
Reference Data
Protein Families	Druggable Genome, Transcription Factors

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