Plasminogen (PLG) Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI4F5]

Specifications

Product Data
Clone Name	OTI4F5
Applications	IHC
Recommend Dilution	IHC 1:500
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Human recombinant protein fragment corresponding to amino acids 301-586 of human PLG (NP_000292) produced in E.coli.
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	0.5 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Biotin
Storage Condition	Store at -20°C as received.
Predicted Protein Size	90.58 kDa
Gene Name	plasminogen
Database Link	NP_000292 Entrez Gene 5340 Human UniProt ID P00747
Background	The protein encoded by this gene is a secreted blood zymogen that is activated by proteolysis and converted to plasmin and angiostatin. Plasmin dissolves fibrin in blood clots and is an important protease in many other cellular processes while angiostatin inhibits angiogenesis. Defects in this gene are likely a cause of thrombophilia and ligneous conjunctivitis. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009]
Synonyms	DKFZp779M0222
Reference Data
Protein Families	Druggable Genome, Protease, Secreted Protein
Protein Pathways	Complement and coagulation cascades, Neuroactive ligand-receptor interaction

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