TRAF5 Mouse Monoclonal Antibody [Clone ID: OTI7A3]

Specifications

Product Data
Clone Name	OTI7A3
Applications	WB
Recommend Dilution	WB 1:500
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Human recombinant protein fragment corresponding to amino acids 334-557 of human TRAF5 (NP_004610) produced in E.coli.
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	1 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	64.2 kDa
Gene Name	TNF receptor associated factor 5
Database Link	NP_004610 Entrez Gene 7188 Human UniProt ID O00463
Background	The scaffold protein encoded by this gene is a member of the tumor necrosis factor receptor-associated factor (TRAF) protein family and contains a meprin and TRAF homology (MATH) domain, a RING-type zinc finger, and two TRAF-type zinc fingers. TRAF proteins are associated with, and mediate signal transduction from members of the TNF receptor superfamily. This protein is one of the components of a multiple protein complex which binds to tumor necrosis factor (TNF) receptor cytoplasmic domains and mediates TNF-induced activation. Alternate transcriptional splice variants have been characterized. [provided by RefSeq, Jul 2008]
Synonyms	MGC:39780; RNF84
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Pathways in cancer, Small cell lung cancer

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