GTP cyclohydrolase 1 (GCH1) Mouse Monoclonal Antibody [Clone ID: OTI5A1]
CAT#: TA810265
GCH1 mouse monoclonal antibody,clone OTI5A1
Size: 30 ul
Formulation: Carrier-Free
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CNY 1,999.00
CNY 2,700.00
CNY 300.00
CNY 1,430.00
CNY 3,080.00
CNY 3,080.00
Specifications
Product Data | |
Clone Name | OTI5A1 |
Applications | IHC, WB |
Recommend Dilution | WB 1:2000, IHC 1:500 |
Reactivity | Human, Mouse, Rat |
Host | Mouse |
Clonality | Monoclonal |
Immunogen | Full length human recombinant protein of human GCH1 (NP_001019195) produced in E.coli. |
Formulation | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
Concentration | 1 mg/ml |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C as received. |
Predicted Protein Size | 27.7 kDa |
Gene Name | GTP cyclohydrolase 1 |
Database Link | |
Background | This gene encodes a member of the GTP cyclohydrolase family. The encoded protein is the first and rate-limiting enzyme in tetrahydrobiopterin (BH4) biosynthesis, catalyzing the conversion of GTP into 7,8-dihydroneopterin triphosphate. BH4 is an essential cofactor required by aromatic amino acid hydroxylases as well as nitric oxide synthases. Mutations in this gene are associated with malignant hyperphenylalaninemia and dopa-responsive dystonia. Several alternatively spliced transcript variants encoding different isoforms have been described; however, not all variants give rise to a functional enzyme. [provided by RefSeq, Jul 2008] |
Synonyms | DYT5; DYT5a; DYT14; GCH; GTP-CH-1; GTPCH1; HPABH4B |
Reference Data | |
Protein Families | Druggable Genome |
Protein Pathways | Folate biosynthesis, Metabolic pathways |
Documents
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
CF810265 | Carrier-free (BSA/glycerol-free) GCH1 mouse monoclonal antibody,clone OTI5A1 |
CNY 3,999.00 |
|
TA810265AM | GCH1 mouse monoclonal antibody,clone OTI5A1, Biotinylated |
CNY 3,990.00 |
|
TA810265BM | GCH1 mouse monoclonal antibody,clone OTI5A1, HRP conjugated |
CNY 3,990.00 |
|
TA810265S | GCH1 mouse monoclonal antibody,clone OTI5A1 |
CNY 800.00 |
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