RHOH Mouse Monoclonal Antibody [Clone ID: OTI9F4]

Specifications

Product Data
Clone Name	OTI9F4
Applications	WB
Recommend Dilution	WB 1:2000
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Human recombinant protein fragment corresponding to amino acids 97-190 of human RHOH(NP_004301) produced in E.coli.
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	1 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	21.1 kDa
Gene Name	ras homolog family member H
Database Link	NP_004301 Entrez Gene 74734 MouseEntrez Gene 305341 RatEntrez Gene 399 Human UniProt ID Q15669
Background	The protein encoded by this gene is a member of the Ras superfamily of guanosine triphosphate (GTP)-metabolizing enzymes. The encoded protein is expressed in hematopoietic cells, where it functions as a negative regulator of cell growth and survival. This gene may be hypermutated or misexpressed in leukemias and lymphomas. Chromosomal translocations in non-Hodgkin's lymphoma occur between this locus and B-cell CLL/lymphoma 6 (BCL6) on chromosome 3, leading to the production of fusion transcripts. Alternative splicing in the 5' untranslated region results in multiple transcript variants that encode the same protein. [provided by RefSeq, May 2013]
Synonyms	ARHH; TTF
Reference Data
Protein Families	Transcription Factors
Protein Pathways	Leukocyte transendothelial migration

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