FYCO1 Mouse Monoclonal Antibody (HRP conjugated) [Clone ID: OTI8G7]

Specifications

Product Data
Clone Name	OTI8G7
Applications	WB
Recommend Dilution	WB 1:2000
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Human recombinant protein fragment corresponding to amino acids 1102-1187 of human FYCO1(NP_078789) produced in E.coli.
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol.
Concentration	0.5 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	HRP
Storage Condition	Store at -20°C as received.
Predicted Protein Size	166.8 kDa
Gene Name	FYVE and coiled-coil domain containing 1
Database Link	NP_078789 Entrez Gene 79443 Human UniProt ID Q9BQS8
Background	This gene encodes a protein that contains a RUN domain, FYVE-type zinc finger domain and Golgi dynamics (GOLD) domain. The encoded protein plays a role in microtubule plus end-directed transport of autophagic vesicles through interactions with the small GTPase Rab7, phosphatidylinositol-3-phosphate (PI3P) and the autophagosome marker LC3. Mutations in this gene are a cause of autosomal recessive congenital cataract-2 (CATC2). [provided by RefSeq, Dec 2011]
Synonyms	CATC2; CTRCT18; RUFY3; ZFYVE7
Reference Data

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