XPB (ERCC3) Mouse Monoclonal Antibody (HRP conjugated) [Clone ID: OTI6H8]

Specifications

Product Data
Clone Name	OTI6H8
Applications	IHC, WB
Recommend Dilution	WB 1:500, IHC 1:1000
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Human recombinant protein fragment corresponding to amino acids 191-436 of human ERCC3 (NP_000113) produced in E.coli.
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol.
Concentration	0.5 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	HRP
Storage Condition	Store at -20°C as received.
Predicted Protein Size	89.1 kDa
Gene Name	ERCC excision repair 3, TFIIH core complex helicase subunit
Database Link	NP_000113 Entrez Gene 13872 MouseEntrez Gene 291703 RatEntrez Gene 2071 Human UniProt ID P19447
Background	ERCC3 is an ATP-dependent DNA helicase that functions in nucleotide excision repair and complements xeroderma pigmentosum group B mutations. It also is the 89 kDa subunit of basal transcription factor 2 (TFIIH) and thus functions in class II transcription. [provided by RefSeq, Jul 2008]
Synonyms	BTF2; GTF2H; RAD25; Ssl2; TFIIH; TTD2; XPB
Reference Data
Protein Families	Druggable Genome, Transcription Factors
Protein Pathways	Nucleotide excision repair

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