GEF H1 (ARHGEF2) Mouse Monoclonal Antibody [Clone ID: OTI5F2]

Specifications

Product Data
Clone Name	OTI5F2
Applications	FC, WB
Recommend Dilution	WB 1:2000
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Full length human recombinant protein of human ARHGEF2 (NP_004714) produced in HEK293T cell.
Formulation	Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method	For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	108.1 kDa
Gene Name	Rho/Rac guanine nucleotide exchange factor 2
Database Link	NP_004714 Entrez Gene 16800 MouseEntrez Gene 310635 RatEntrez Gene 9181 Human UniProt ID Q92974
Background	Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form complex with G proteins and stimulate rho-dependent signals. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jun 2009]
Synonyms	GEF; GEF-H1; GEFH1; LFP40; P40
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Pathogenic Escherichia coli infection

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